TEAM

Félix Busqué Sánchez

Dr. Félix Busqué studied Chemistry at the Universitat Autònoma de Barcelona (UAB), Spain, where he obtained his B.Sc. degree in 1991 and his Ph.D. degree in 1997 under the supervision of Professors Pere de March and Marta Figueredo in the research group of Prof. Josep Font, on the topic of [3+2] cycloadditions of nitrones to α,β-unsaturated carbonyl compounds, towards a general and stereoselective synthesis of Securinega alkaloids. Next, he carried out a two-years postdoctoral stage at the University of California Santa Cruz in the laboratories of Prof. Joseph Konopelski working on a medicinal chemistry project related with the development of new peptide mimetics designed to act as blockers of breast cancer metastasis. Back at the UAB, after several postdoctoral contracts working on total synthesis of natural products, he was awarded with a Ramón y Cajal research contract for 5 years, focused on the development of biomimetic functional materials based on catechol compounds. In 2009 he obtained a permanent position as Associate Professor at UAB. His scientific interests focus on two main interdisciplinary research lines, in collaboration with other research groups; one of them focused on the development of functional materials based on catechol compounds, and another centered in different projects of medicinal chemistry, highlighting one aimed to achieve remote control of neuronal activity with synthetic molecular switches.

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Selected publications

  1. Saiz-Poseu, J.; Mancebo-Aracil, J.; Nador, F.; Busqué, F.; Ruiz-Molina, D. The chemistry behind Catechol-Based adhesion. Angew. Chem. Int. Ed. 2019, 58, 696-714. https://doi.org/10.1002/anie.201801063
  2. Cabre, G.; Garrido-Charles, A.; Moreno, M.; Bosch, M.; Porta-de-la-Riva, M.; Krieg, M.; Gascon-Moya, M.; Camarero, N.; Gelabert, R.; Lluch, J.-M.; Busque, F.; Hernando, J.; Gorostiza, P.; Alibes, R. Rationally designed azobenzene photoswitches for efficient two-photon neuronal excitation. Nat. Commun. 2019,10, 907. https://doi.org/10.1038/s41467-019-08796-9
  3. Solórzano, R.; Tort, O.; García-Pardo, J.; Escribà, T.; Lorenzo, J.; Arnedo, M.; Ruiz-Molina, D.; Alibés, R.; Busqué, F.; Novio, F. Versatile Iron-Catechol based Nanoscale Coordination Polymers Antiretroviral Ligand Functionalization and their use as Efficient Carriers in HIV/AIDS Therapy. Biomater. Sci. 2019, 7, 178-186. https://doi.org/10.1039/c8bm01221k
  4. Domínguez-Pérez, B.; Ferrer, E.; Figueredo, E.; Maréchal, J.-D.; Balzarini, J.; Alibés, R.; Busqué, F. Synthesis of novel nucleoside analogues built on a bicyclo[4.1.0]heptane scaffold. J. Org. Chem. 2015, 80, 9495-9505. https://doi.org/10.1021/acs.joc.5b01413
  5. Saiz-Poseu, J.; Sedó, J.; García, B.; Benaiges, C.; Parella, T.; Alibés, R.; Hernando, J.; Busqué, F.; Ruiz-Molina, D. Versatile Nanostructured Materials via Direct Reaction of Functionalized Catechols. Adv. Mat. 2013, 25, 2066-2070. https://doi.org/10.1002/adma.201204383
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